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09:15
- 09:30 |
Welcome
Address Rachel
WATSON, Chair of Scientific Committee, Singapore |
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09:30
- 11:00 |
SESSION
1. TISSUE INTEGRITY Chairs: Carine BONNARD & Jiah Shin CHIN (ASRL,
Singapore) |
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09:30
- 10:00 |
Exploiting endothelial plasticity in understanding
and modelling skin diseases Kiarash KHOSROTEHRANI (University of Queensland, Australia) |
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10:00
- 10:15 |
Abstract selected talk A
role for keratinocyte Arginase in skin wound healing and barrier function Denis
SZONDI (University of Manchester, UK) |
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10:15
- 10:30 |
Abstract selected talk Polyamine metabolism is pivotal in the self-limiting
control of wound healing Meng SHI (ASRL,
Singapore) |
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10:30
- 11:00 |
Defining skin integrity: Insights from across the pigmentary spectrum Abigail LANGTON (University of Manchester, UK) |
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11:00
- 11:30 |
TEA
BREAK |
|
11:30
- 13:00 |
SESSION
2. SKIN HEALTH & AGEING Chairs:
Sophie BELLANGER (ASRL, Singapore) & Rachel WATSON
(ASRL & SRIS, Singapore) |
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11:30
- 12:00 |
Altering
cell mechanics to inhibit melanoma cell migration, invasion and metastasis Nikolas
HAASS (University of Queensland, Australia) |
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12:00
- 12:15 |
Abstract selected talk Delineating the chain of events that trigger
cellular senescence in Hutchinson-Gilford progeria Mattheus Xing Rong FOO (ASRL, Singapore) |
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12:15
- 12:30 |
Abstract selected talk Identification of novel targets regulating air
pollution induced hyperpigmentation Rachel PHUA (ASRL, Singapore) |
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12:30
- 13:00 |
Polyamines:
Novel Regulators of Human Epidermal Pigmentation Leah VARDY (ASRL, Singapore) |
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13:00
- 14:00 |
LUNCH
BREAK |
|
14:00
- 15:45 |
SESSION
3. MOLECULAR SIGNALLING & INFLAMMATION Chairs:
Kenneth LAY & John COMMON (ASRL,
Singapore) |
|
14:00
- 14:30 |
Animal
models for Psoriasis Nicole
WARD (Vanderbilt University Medical Center, US) |
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14:30
- 14:45 |
Abstract selected talk The
spatial proteome of psoriasis Marianne
LOVENDORF (Copenhagen University, Denmark) |
|
14:45
- 15:00 |
Abstract selected talk Beyond the Surface: 1L-17, miR-101 and EZH2 - a
psoriatic tale Gowtham SUBRAMANIAN (ASRL, Singapore) |
|
15:00
- 15:15 |
Abstract selected talk Epidermis-derived lactate promotes sterile
inflammation and psoriatic skin disease by inducing metabolic rewiring in macrophages Uttkarsh AYYANGAR (INSTEM,
India) |
|
15:15
- 15:45 |
The ZAKalpha-NLRP1 axis in skin inflammation Franklin ZHONG (NTU, LKCM, Singapore) |
|
15:45
- 16:30 |
KEYNOTE
LECTURE Chair:
Rachel WATSON (ASRL, SRIS, Singapore) Discovery, diagnosis and doing something different
for people with inherited skin diseases John MCGRATH (King s College, UK) |
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16:30
- 18:00 |
POSTER
SESSION & NETWORKING |
|
09:00
- 10:30 |
SESSION
4. TISSUE MICROENVIRONMENT Chairs: Birgit LANE (SRIS, Singapore) & Aishwarya
Sridharan (ASRL, Singapore) |
|
09:00
- 9:30 |
Spatial regulation of extracellular matrix turnover
rates guides macro-scale organ shape in mouse skin Hironubu FUJIWARA (RIKEN, Japan) |
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09:30
- 9:45 |
Abstract selected talk Electrical Stimulation Therapy accelerates epidermal
repair in an in-vitro 3D wound model by promoting MMP1-mediated cell
migration toward denuded dermis Carine BONNARD (ASRL, Singapore) |
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09:45
- 10:00 |
Abstract selected talk TGF-β1 secretion via keratinocyte-derived
extracellular vesicles drives fibroblast-induced tissue contraction Khek-Chian THAM (ASRL, Singapore) |
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10:00
- 10:30 |
Uncovering the role of resident skin macrophages in
development and disease Srikala RAGHAVAN (ASRL, Singapore) |
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10:30
- 11:00 |
TEA
BREAK |
|
11:00
- 12:45 |
SESSION
5. INFLAMMATORY SKIN DISEASE Chairs:
Hazel OON (National Skin Centre) & Baptiste JANELA (NTU, LKCM, Singapore) |
|
11:00
- 11:30 |
Newly
identification of a CXCR6+ pathogenic skin-resident
CD4+ T cell subset in a mouse model of allergic dermatitis that requires
CXCL16 for its maintenance Kenji
KABASHIMA (University of Kyoto, Japan) |
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11:30
- 11:45 |
Abstract selected talk Epidermal disruption induced by Vulcanodium
rugosum toxin is rescued by gene knockout of ZAKα Stephen WEARNE (ASRL, Singapore) |
|
11:45
- 12:00 |
Abstract selected talk Deciphering the immune mechanisms of autoreactive B
cells in Pemphigus Baptiste Janela (NTU, LKCM, Singapore) |
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12:00
- 12:15 |
Abstract selected talk The ribotoxic stress
response drives inflammation and epidermal thickening in UV-irradiated skin
in vivo Anna Constance VIND (University of Copenhagen) |
|
12:15
- 12:45 |
Beyond the Silence: Decoding microRNA-335 dynamics
in Atopic Dermatitis Prabha SAMPATH (ASRL, Singapore) |
|
12:45
- 14:00 |
LUNCH
BREAK |
|
14:00
- 15:45 |
SESSION 6.
TISSUE IMAGING Chairs:
Dinish U. S (ASRL, Singapore) & Sierin LIM (NTU) |
|
14:00
- 14:30 |
Ionic
liquids for transdermal drug delivery Samir
MITRAGOTRI (Harvard University, USA) |
|
14:30
- 14:45 |
Abstract selected talk Quantitative biomechanical analysis assessing skin
inflammatory conditions using handheld confocal Raman spectroscopy Keertana VINOD RAM (ASRL, Singapore) |
|
14:45
- 15:00 |
Abstract selected talk Elucidating the role of nuclear mechanotransduction
in homeostasis and fibrosis Yin Loon LEE (ASRL, Singapore) |
|
15:00
- 15:30 |
Innovation
in biophotonics technologies for objective
assessment of dermatological conditions Malini OLIVO (ASRL, Singapore) |
|
15:30
- 17:00 |
POSTER
SESSION |
|
18:30 |
CONFERENCE
DINNER |
|
09:00
- 10:30 |
SESSION
7. HOST-MICROBE INTERACTION Chairs: Thomas DAWSON (ASRL, Singapore) & Tarun
CHOPRA (L Oreal, Singapore) |
|
09:00
- 9:30 |
Dermal
fat, an important deep skin layer in host defense
and repair Ling-Juan ZHANG (Xiamen University, China) |
|
09:30
- 9:45 |
Abstract selected talk Impact of polyketide synthase on Malassezia's PUFA
metabolism and its consequences on skin-host dynamics Shi Mun LEE (ASRL, Singapore) |
|
09:45
- 10:00 |
Abstract selected talk Genetic barrier dysfunction drives skin inflammation
during atopy and cutaneous pathogenic colonization Ying Shiang LIM (ASRL, Singapore) |
|
10:00
- 10:30 |
Unlocking
microbiome medicine for the human skin Viduthalai RASHEEDKHAN REGINA (NTU, Singapore) |
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10:30
- 11:00 |
COFFEE
BREAK |
|
11:00
- 12:30 |
SESSION
8. APPENDAGES Chairs:
Carlos CLAVEL (ASRL, Singapore) & Etienne
WANG (National Skin Centre, Singapore) |
|
11:00
- 11:30 |
Bioactive
lipids mediating epidermal barrier functionality Anna
NICOLAOU (University of Manchester, UK) |
|
11:30
- 11:45 |
Abstract selected talk The
dynamic interplay between dermal adipocyte lineage cells and macrophages in
regulating acne-mediated skin inflammation and fibrosis Yiman LIU (Xiamen
University) |
|
11:45
- 12:00 |
Abstract selected talk Investigating the intrinsic regulation of the hair
follicle stem cell niche by MEF2C Tracy Zhijun TIEN (ASRL,
Singapore) |
|
The latest and greatest on sebaceous glands Maurice VAN
STEENSEL (NTU, LKCM, Singapore) |
|
|
12:30
- 14:00 |
LUNCH
BREAK |
|
14:00
- 15:45 |
SESSION 9. EMERGING TECHNOLOGIES Chairs: Liang KUN (ASRL, Singapore)
& Anna NICOLAOU (Manchester University, UK) |
|
14:00
- 14:30 |
How can mass spectrometry-based proteomics
help us elucidate mechanisms of disease in dermatology? Beatrice
DYRING-ANDERSEN (University of Copenhagen, Denmark) |
|
14:30
- 14:45 |
Nanopore
sequencing enables allelic phasing of FLG loss-of-function variants,
intragenic copy number variation and methylation status in AD and Icthyosis Vulgaris Colin WONG (ASRL, Singapore) |
|
14:45
- 15:00 |
A sustainable
strategy for generating highly stable human skin equivalents based on fish collagen Shi Hua TAN (ASRL, Singapore) |
|
Going beyond
the surface: transepidermal microbiome microbiome sampling using 3D-printed microprojection
arrays Kun LIANG (ASRL, Singapore) |
|
|
Jay SHIN (Genome
Institute of Singapore) |
|
|
15:45 |