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	SATURDAY 24TH MARCH - DAY 4
08.30 – 09:00	REGISTRATION
09.00 – 10.45	SESSION 10: SKIN BARRIER DEVELOPMENT & INTEGRITY Chairs: So Yun CHO, Director of Board of Members of KSBR Leah VARDY, Institute of Medical Biology, Singapore
09.00 – 09.30	Akiharu Kubo, Keio University School of Medicine, Tokyo, Japan Tight but dynamic: The sophisticated barrier system of mammalian skin
09.30 – 09.45	Li HE, Institute of Dermatology & Venereology of Yunnan province, Kunming, China MicroRNA-224-5p induced claudin-5 deficiency contributes to defective permeability barrier in sensitive skin
09.45 – 10.00	Kento Kitada, DUKE-NUS Medical School, Singapore Increased glucocorticoid hormone actions via melanocortin 3 receptor deletion induce skin-specific Na+ and water loss
10.00 – 10.15	Anisa RAHIM, Institute of Medical Biology, Singapore Unravelling gene regulation in the epidermis during differentiation
10.15 – 10.45	Florent GINHOUX, Singapore Immunology Network, Singapore Human dendritic cells: From development to functions.
10.45 – 11.15	Morning tea break
11.15 – 13.00	SESSION 11: Skin Barrier & THE IMMUNE SYSTEM Chairs: Chih-Hung (Abel) LEE, Kaohsiung Chang Gung Memorial Hospital, Taiwan Kenji KABASHIMA, Department of Dermatology, University of Kyoto, Japan
11.15 – 11.45	Chang Ook PARK, Yonsei University College of Medicine, Seoul, Korea Tissue-resident memory T cells as an immune barrier
11.45 – 12.00	Rintaro Shibuya, Kyoto University Graduate School of Medicine, Japan Complement activation increases susceptibility to surfactant-induced irritant contact dermatitis
12.00 – 12.15	Anand Kumar Andiappan, Singapore Immunology Network, Singapore Whole transcriptome analysis of peripheral blood reveals strong proinflammatory signatures associated with skin relevant FLG mutants
12.15 – 12.30	Jiajia MA, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore A proteolytic regulator of epidermal integrity and inflammation
12.30 – 13.00	Franklin ZHONG, Institute of Medical Biology, Singapore NLRP1 inflammasome in skin inflammation and cancer susceptibility
13.00	END OF CONFERENCE