* subject to changes
Timings are in Singapore time (UTC+8); please adjust to our local timings also considering day-light-saving timings
Timings are in Singapore time (UTC+8); please adjust to our local timings also considering day-light-saving timings
WEDNESDAY, 23rd March - DAY 1
_________________________________________________________________________
WELCOME & OPENING OF SYMPOSIUM
13:00 – 13:10 WELCOME ADDRESS
Conference Chairs
Srikala RAGHAVAN & Carlos CLAVEL, A*STAR Skin Research Labs, Singapore
_________________________________________________________________________
SESSION 1. SKIN BIOINSPIRED ENGINEERING
Chairs: Freda LIM, Institute of High Performance Computing, A*STAR, Singapore & Peng CHEN, Nanyang Technological University, Singapore
13:10 – 13:35 The feel of my skin: Connecting sensorial perception to topical
formulations
Reinhold DAUSKARDT, Stanford University, US
13:35 – 14:00 Ligand nanospacing modulates keratinocyte collective
migration
Jennifer YOUNG, National University of Singapore
14:00 – 14:12 Selected abstract
Bioactive polymeric scaffolds for skin regeneration
Yew Chin TEO, Institute of Materials Research and
Engineering, A*STAR Singapore
14:12 – 14:24 Selected abstract
Photoactive bacterial cellulose patches as microbial barriers
for prevention of intraoral wound infections
Juhi SINGH, Nanyang Technological University, Singapore
14:24 – 14:49 Design of bioadhesive barrier films preventing microorganism
migration
Terry STEELE, Nanyang Technological University, Singapore
14:49 – 15:14 Electronic skins and biomedical applications
Benjamin TEE, National University of Singapore
15:14 – 15:45 BREAK
_________________________________________________________________________
SESSION 2. STEMCELLS AND HOMEOSTASIS
Chairs: Srikala RAGHAVAN & Chin Yan LIM, A*STAR Skin Research Labs, Singapore
15:45 – 16:10 A peek into human skin pericyte heterogeneity
Pritinder KAUR, Curtin University, Perth, Australia
16:10 – 16:35 What we know about sebaceous gland progenitor cells
Maurice VAN STEENSEL, LKCM, Singapore
16:35 – 17:00 Mechanisms of skin aging
Salvador AZNAR BENITAH, Institute for Research
in Biomedicine, Spain
17:00 – 17:12 Selected abstract
The Role of Sox6 in stem cell heterogeneity and tissue regeneration in skin
Seona LEE, Cornell University, USA
17:12– 17:24 Selected abstract
aPKC controlled actomyosin contractility regulates keratin
network organization and stratified epithelial integrity
Matthias RÜBSAM, University of Cologne, Germany
17:24 – 17:36 Selected abstract
Defining the molecular and cellular mechanisms of tissue
repair upon lineage ablation in the skin epidermis
Rahul SARATE, Université Libre de Bruxelles, Belgium
17:36 – 17:48 Selected abstract
BAZ2A, an epigenetic gatekeeper regulating epidermal
proliferation and tumorigenesis
Fathima Rifkhana SHAH JAHAN, Skin Research Institute of
Singapore
17:48– 18:13 Multiple levels of heterogeneity contribute to robust
homeostasis of adult interfollicular epidermis
Doina TUMBAR, Cornell University, Ithaca, USA
18:15 END OF DAY 1
WELCOME & OPENING OF SYMPOSIUM
13:00 – 13:10 WELCOME ADDRESS
Conference Chairs
Srikala RAGHAVAN & Carlos CLAVEL, A*STAR Skin Research Labs, Singapore
_________________________________________________________________________
SESSION 1. SKIN BIOINSPIRED ENGINEERING
Chairs: Freda LIM, Institute of High Performance Computing, A*STAR, Singapore & Peng CHEN, Nanyang Technological University, Singapore
13:10 – 13:35 The feel of my skin: Connecting sensorial perception to topical
formulations
Reinhold DAUSKARDT, Stanford University, US
13:35 – 14:00 Ligand nanospacing modulates keratinocyte collective
migration
Jennifer YOUNG, National University of Singapore
14:00 – 14:12 Selected abstract
Bioactive polymeric scaffolds for skin regeneration
Yew Chin TEO, Institute of Materials Research and
Engineering, A*STAR Singapore
14:12 – 14:24 Selected abstract
Photoactive bacterial cellulose patches as microbial barriers
for prevention of intraoral wound infections
Juhi SINGH, Nanyang Technological University, Singapore
14:24 – 14:49 Design of bioadhesive barrier films preventing microorganism
migration
Terry STEELE, Nanyang Technological University, Singapore
14:49 – 15:14 Electronic skins and biomedical applications
Benjamin TEE, National University of Singapore
15:14 – 15:45 BREAK
_________________________________________________________________________
SESSION 2. STEMCELLS AND HOMEOSTASIS
Chairs: Srikala RAGHAVAN & Chin Yan LIM, A*STAR Skin Research Labs, Singapore
15:45 – 16:10 A peek into human skin pericyte heterogeneity
Pritinder KAUR, Curtin University, Perth, Australia
16:10 – 16:35 What we know about sebaceous gland progenitor cells
Maurice VAN STEENSEL, LKCM, Singapore
16:35 – 17:00 Mechanisms of skin aging
Salvador AZNAR BENITAH, Institute for Research
in Biomedicine, Spain
17:00 – 17:12 Selected abstract
The Role of Sox6 in stem cell heterogeneity and tissue regeneration in skin
Seona LEE, Cornell University, USA
17:12– 17:24 Selected abstract
aPKC controlled actomyosin contractility regulates keratin
network organization and stratified epithelial integrity
Matthias RÜBSAM, University of Cologne, Germany
17:24 – 17:36 Selected abstract
Defining the molecular and cellular mechanisms of tissue
repair upon lineage ablation in the skin epidermis
Rahul SARATE, Université Libre de Bruxelles, Belgium
17:36 – 17:48 Selected abstract
BAZ2A, an epigenetic gatekeeper regulating epidermal
proliferation and tumorigenesis
Fathima Rifkhana SHAH JAHAN, Skin Research Institute of
Singapore
17:48– 18:13 Multiple levels of heterogeneity contribute to robust
homeostasis of adult interfollicular epidermis
Doina TUMBAR, Cornell University, Ithaca, USA
18:15 END OF DAY 1
THURSDAY, 24th March - DAY 2
________________________________________________________________________
SESSION 3. RAPID-FIRE TALKS I
Chairs: Leah VARDY & Aishwarya SRIDHARAN, A*STAR Skin Research Labs, Singapore
11:00 – 12:30 Fire-talks (5 mins each speaker)
12:30 – 13:00 BREAK
_________________________________________________________________________________
SESSION 4. SKIN PIGMENTATION & APPENDAGES
Chairs: Carlos CLAVEL, A*STAR Skin Research Labs, Singapore & Sierin LIM, Nanyang Technological University, Singapore
13:00 – 13:25 Avian pigment pattern formation
Cheng-Ming CHUONG, University of Southern California, USA
13:25 – 13:37 Selected abstract
A multi-omics approach to identifying factors involved in
hair follicle growth and development
Nikolaos PANTELIREIS, A*STAR Skin Research Labs, Singapore
13:37 – 13:49 Selected abstract
Investigation of the action mechanisms of topical contact
immunotherapy in alopecia areata
Yohei NATSUAKI, A*STAR Skin Research Labs, Singapore
13:49 – 14:01 Selected abstract
Symmetry breaking of tissue mechanics in wound induced
hair follicle regeneration of laboratory and spiny mice
Hans I-Chen HARN, University of Southern California, USA
14:01 – 14:26 Mesenchymal stem cell heterogeneity in the hair follicle
David ENSHELL-SEIJFFERS, Bar Ilan University, Israel
14:26 – 14:51 Effect of particulate matter on skin pigmentation
Sang Ho OH, Severance Hospital, Seoul, South Korea
14:51 – 15:30 BREAK
________________________________________________________________________
SESSION 5. DISEASE & THERAPEUTICS
Chairs: Hong Liang TEY, National Skin Centre, NHG, Singapore & Franklin ZHONG, LKCMedicine, Nanyang Technological University, Singapore
15:30 – 15:55 Defining the mechanisms of skin expansion at single cell
resolution
Cedric BLANPAIN, Université Libre de Bruxelles, Belgium
15:55 – 16:07 Selected abstract
Spontaneous generation of autoantibodies to bullous
pemphigoid antigens in Treg-deficient mice and humans
Ken MURAMATSU, Hokkaido University, Japan
16:07 – 16:19 Selected abstract
Molecular basis of vasculature defects in a mouse model of the fibrotic skin disease scleroderma
Dyuti SAHA, Institute for Stem Cell Science and Regenerative Medicine, India
16:19 – 16:31 Selected abstract
MiR-149: a microRNA regulating keratinocyte immune
responses in psoriasis
Enikö SONKOLY, Karolinska Institutet, Sweden
16:31 – 16:43 Selected abstract
A nuclear import protein variant is a trigger and driver of
NLRP1 inflammasome in human skin
Kenneth LAY, Genome Institute of Singapore, A*STAR,
Singapore
16:43 – 17:08 Kindlin degradation drives focal adhesion disassembly at
mitotic entry
Reinhard FÄSSLER, Max Planck Institute of Biochemistry,
Germany
17:08 – 17:33 Skin diseases and therapeutics: Biotherapeutic approaches in
Atopic Dermatitis
Elizabeth THAM, National University of Singapore
17:33 – 17:48 Beauty is more than skin deep: Skin imaging from micro to
macro view
Lai Guan NG, Singapore Immunology Network, Singapore
17:50 END OF DAY 2
SESSION 3. RAPID-FIRE TALKS I
Chairs: Leah VARDY & Aishwarya SRIDHARAN, A*STAR Skin Research Labs, Singapore
11:00 – 12:30 Fire-talks (5 mins each speaker)
- Carine Bonnard, A*STAR Skin Research Labs, Singapore
- Ruth Chai, IMCB, Singapore
- Smarajit Chakrabory, IMCB, Singapore
- Edries Hajam, inStem, Bangalore, India
- Justine Lengrand, Universite Libre de Bruxelles, Belgium
- Thomas Mortimer, Institute for Research in Biomedicine, Spain
- Rachel Phua, A*STAR Skin Research Labs, Singapore
- Erna Raja, IRCMS Kumamoto University, Japan
- Meng Shi, A*STAR Skin Research Labs, Singapore
- Xue Hui Tan, A*STAR Skin Research Labs, Singapore
- Benjamin Ungar, Icahn School of Medicine at Mount Sinai, US
- Colin Wong, A*STAR Skin Research Labs, Singapore
12:30 – 13:00 BREAK
_________________________________________________________________________________
SESSION 4. SKIN PIGMENTATION & APPENDAGES
Chairs: Carlos CLAVEL, A*STAR Skin Research Labs, Singapore & Sierin LIM, Nanyang Technological University, Singapore
13:00 – 13:25 Avian pigment pattern formation
Cheng-Ming CHUONG, University of Southern California, USA
13:25 – 13:37 Selected abstract
A multi-omics approach to identifying factors involved in
hair follicle growth and development
Nikolaos PANTELIREIS, A*STAR Skin Research Labs, Singapore
13:37 – 13:49 Selected abstract
Investigation of the action mechanisms of topical contact
immunotherapy in alopecia areata
Yohei NATSUAKI, A*STAR Skin Research Labs, Singapore
13:49 – 14:01 Selected abstract
Symmetry breaking of tissue mechanics in wound induced
hair follicle regeneration of laboratory and spiny mice
Hans I-Chen HARN, University of Southern California, USA
14:01 – 14:26 Mesenchymal stem cell heterogeneity in the hair follicle
David ENSHELL-SEIJFFERS, Bar Ilan University, Israel
14:26 – 14:51 Effect of particulate matter on skin pigmentation
Sang Ho OH, Severance Hospital, Seoul, South Korea
14:51 – 15:30 BREAK
________________________________________________________________________
SESSION 5. DISEASE & THERAPEUTICS
Chairs: Hong Liang TEY, National Skin Centre, NHG, Singapore & Franklin ZHONG, LKCMedicine, Nanyang Technological University, Singapore
15:30 – 15:55 Defining the mechanisms of skin expansion at single cell
resolution
Cedric BLANPAIN, Université Libre de Bruxelles, Belgium
15:55 – 16:07 Selected abstract
Spontaneous generation of autoantibodies to bullous
pemphigoid antigens in Treg-deficient mice and humans
Ken MURAMATSU, Hokkaido University, Japan
16:07 – 16:19 Selected abstract
Molecular basis of vasculature defects in a mouse model of the fibrotic skin disease scleroderma
Dyuti SAHA, Institute for Stem Cell Science and Regenerative Medicine, India
16:19 – 16:31 Selected abstract
MiR-149: a microRNA regulating keratinocyte immune
responses in psoriasis
Enikö SONKOLY, Karolinska Institutet, Sweden
16:31 – 16:43 Selected abstract
A nuclear import protein variant is a trigger and driver of
NLRP1 inflammasome in human skin
Kenneth LAY, Genome Institute of Singapore, A*STAR,
Singapore
16:43 – 17:08 Kindlin degradation drives focal adhesion disassembly at
mitotic entry
Reinhard FÄSSLER, Max Planck Institute of Biochemistry,
Germany
17:08 – 17:33 Skin diseases and therapeutics: Biotherapeutic approaches in
Atopic Dermatitis
Elizabeth THAM, National University of Singapore
17:33 – 17:48 Beauty is more than skin deep: Skin imaging from micro to
macro view
Lai Guan NG, Singapore Immunology Network, Singapore
17:50 END OF DAY 2
FRIDAY, 25th March - DAY 3
_________________________________________________________________________
SESSION 6. RAPID-FIRE TALKS II
Chairs: Leah VARDY & Aishwarya SRIDHARAN, A*STAR Skin Research Labs, Singapore
10:30 – 12:00 Fire-talks (5 mins each speaker)
13. Ya-Chen Liang, University of Southern California. US
14. Ryan Lim, A*STAR Skin Research Labs, Singapore
15. Isha Rana, inStem, Bangalore, India
16. Chew Teng Tan, A*STAR Skin Research Labs, Singapore
17. Christina Tan, A*STAR Skin Research Labs, Singapore
18. Tracy Tien, A*STAR Skin Research Labs, Singapore
19. Bach Le, BTI A*STAR, Singapore
20. Maud Debaugnies, Universite libre de Buxelles, Belgium
21. Christabel Dube, A*STAR Skin Research Labs, Singapore
22. Skyler Perot, University of Cologne, Germany
23. Hanyin Zhang, University of Cologne, Germany
24. Mark Tuffley, Private OMF Surgical Practice, Australia
12:00 – 12:30 BREAK
_______________________________________________________________________
Industry sponsored session on SINGLE CELL TECHNOLOGIES FOR SKIN RESEARCH
Chairs: Ram DASGUPTA, Genome Institute of Singapore, A*STAR & John COMMON, A*STAR Skin Research Labs, Singapore
12:30 – 12:40 Introduction to single cell technologies
Tumor evolution: through the looking glass of single cells
Ram DasGupta, Genome Institute of Singapore, A*STAR,
Singapore
12:40 – 12:55 Presentation sponsored by 10x Genomics
Exploring Single Cell Transcriptomics and Spatial Transcriptomics of the human Skin
Jay W SHIN, Genome Institute of Singapore
12:55 – 13:10 Presentation sponsored by Akoya Biosciences
Spatial analysis and single cell omics: from discovery to
diagnosis
James Fraser, Akoya Biosciences
13:10 – 13:25 Presentation sponsored by BD Biosciences
Scratching the surface of skin biology using single-cell transcriptomics
Nicholas DEPATIE, BD Biosciences
13:25 – 13:40 Presentation sponsored by Nanostring
Revolutionizing Biology with Nanostring spatial Biology
solutions
Marshall FETERL, Nanostring
________________________________________________________________________________
SESSION 7. SKIN REGENERATION AND AGEING
Chairs: Oliver Dreesen, A*STAR Skin Research Labs & Yizhen NG, Skin Research Institute of Singapore
13:40 – 14:05 Regulation of the skin's antimicrobial defenses
Colin JAMORA, InStem, India
14:05 – 14:17 Selected abstract
Molecular functions of the nuclear lamina in premature cell ageing
Mattheus Xing Rong FOO, A*STAR Skin Research Labs,
Singapore
14:17 – 14:29 Selected abstract
Local IL-17 orchestrates skin aging
Paloma SOLÁ, The Barcelona Institute of Science and
Technology, Spain
14:29 – 14:54 Integrating signalling, adhesion and mechanics in skin
epidermal homeostasis and disease
Carien NIESSEN, University of Cologne, Germany
14:54 – 15:30 BREAK
_________________________________________________________________________
SESSION 8. IMMUNITY & INFECTIONS
Chairs: Baptiste JANELA, A*STAR Skin Research Labs, Singapore & Etienne WANG, National Skin Centre, NHG, Singapore
15:30 – 15:55 Inflammatory skin diseases and upcoming treatments
Emma GUTTMAN YASSKY, Mount Sinai, New York, USA
15:55 – 16:20 Obesity and skin physiology underlying atopic dermatitis -
genetics and beyond
Marie Loh, LKCMed NTU, Singapore
16:20 – 16:32 Selected abstract
Epidermis derived lactic acid augments pro-remodelling fate
acquisition in macrophages during sterile inflammation in
embryonic skin
Uttkarsh AYYANGAR, Institute for Stem Cell Science and
Regenerative Medicine, India
16:32 – 16:44 Selected abstract
Deciphering the molecular functions of skin fungal secretory
proteases
Hao LI, Institute of Molecular and Cell Biology, Singapore
16:44 – 17:09 B cell depletion in pemphigus: a window on B cell
autoimmunity
Philippe MUSETTE, INSERM Bobigny, France
17:09 – 17:34 Immune-epithelial crosstalk in inflammation and tissue
repair
Shruti NAIK, New York University, USA
17:35 POSTER PRIZE AWARD & CLOSING REMARKS
Srikala RAGHAVAN & Carlos CLAVEL, A*STAR Skin Research
Labs, Singapore
John COMMON, President Skin Research Society Singapore
END OF DAY 3 & FAREWELL
SESSION 6. RAPID-FIRE TALKS II
Chairs: Leah VARDY & Aishwarya SRIDHARAN, A*STAR Skin Research Labs, Singapore
10:30 – 12:00 Fire-talks (5 mins each speaker)
13. Ya-Chen Liang, University of Southern California. US
14. Ryan Lim, A*STAR Skin Research Labs, Singapore
15. Isha Rana, inStem, Bangalore, India
16. Chew Teng Tan, A*STAR Skin Research Labs, Singapore
17. Christina Tan, A*STAR Skin Research Labs, Singapore
18. Tracy Tien, A*STAR Skin Research Labs, Singapore
19. Bach Le, BTI A*STAR, Singapore
20. Maud Debaugnies, Universite libre de Buxelles, Belgium
21. Christabel Dube, A*STAR Skin Research Labs, Singapore
22. Skyler Perot, University of Cologne, Germany
23. Hanyin Zhang, University of Cologne, Germany
24. Mark Tuffley, Private OMF Surgical Practice, Australia
12:00 – 12:30 BREAK
_______________________________________________________________________
Industry sponsored session on SINGLE CELL TECHNOLOGIES FOR SKIN RESEARCH
Chairs: Ram DASGUPTA, Genome Institute of Singapore, A*STAR & John COMMON, A*STAR Skin Research Labs, Singapore
12:30 – 12:40 Introduction to single cell technologies
Tumor evolution: through the looking glass of single cells
Ram DasGupta, Genome Institute of Singapore, A*STAR,
Singapore
12:40 – 12:55 Presentation sponsored by 10x Genomics
Exploring Single Cell Transcriptomics and Spatial Transcriptomics of the human Skin
Jay W SHIN, Genome Institute of Singapore
12:55 – 13:10 Presentation sponsored by Akoya Biosciences
Spatial analysis and single cell omics: from discovery to
diagnosis
James Fraser, Akoya Biosciences
13:10 – 13:25 Presentation sponsored by BD Biosciences
Scratching the surface of skin biology using single-cell transcriptomics
Nicholas DEPATIE, BD Biosciences
13:25 – 13:40 Presentation sponsored by Nanostring
Revolutionizing Biology with Nanostring spatial Biology
solutions
Marshall FETERL, Nanostring
________________________________________________________________________________
SESSION 7. SKIN REGENERATION AND AGEING
Chairs: Oliver Dreesen, A*STAR Skin Research Labs & Yizhen NG, Skin Research Institute of Singapore
13:40 – 14:05 Regulation of the skin's antimicrobial defenses
Colin JAMORA, InStem, India
14:05 – 14:17 Selected abstract
Molecular functions of the nuclear lamina in premature cell ageing
Mattheus Xing Rong FOO, A*STAR Skin Research Labs,
Singapore
14:17 – 14:29 Selected abstract
Local IL-17 orchestrates skin aging
Paloma SOLÁ, The Barcelona Institute of Science and
Technology, Spain
14:29 – 14:54 Integrating signalling, adhesion and mechanics in skin
epidermal homeostasis and disease
Carien NIESSEN, University of Cologne, Germany
14:54 – 15:30 BREAK
_________________________________________________________________________
SESSION 8. IMMUNITY & INFECTIONS
Chairs: Baptiste JANELA, A*STAR Skin Research Labs, Singapore & Etienne WANG, National Skin Centre, NHG, Singapore
15:30 – 15:55 Inflammatory skin diseases and upcoming treatments
Emma GUTTMAN YASSKY, Mount Sinai, New York, USA
15:55 – 16:20 Obesity and skin physiology underlying atopic dermatitis -
genetics and beyond
Marie Loh, LKCMed NTU, Singapore
16:20 – 16:32 Selected abstract
Epidermis derived lactic acid augments pro-remodelling fate
acquisition in macrophages during sterile inflammation in
embryonic skin
Uttkarsh AYYANGAR, Institute for Stem Cell Science and
Regenerative Medicine, India
16:32 – 16:44 Selected abstract
Deciphering the molecular functions of skin fungal secretory
proteases
Hao LI, Institute of Molecular and Cell Biology, Singapore
16:44 – 17:09 B cell depletion in pemphigus: a window on B cell
autoimmunity
Philippe MUSETTE, INSERM Bobigny, France
17:09 – 17:34 Immune-epithelial crosstalk in inflammation and tissue
repair
Shruti NAIK, New York University, USA
17:35 POSTER PRIZE AWARD & CLOSING REMARKS
Srikala RAGHAVAN & Carlos CLAVEL, A*STAR Skin Research
Labs, Singapore
John COMMON, President Skin Research Society Singapore
END OF DAY 3 & FAREWELL