* subject to changes
WEDNESDAY, 24th February - DAY 1
Welcome & Opening of Symposium
13:00 – 13:10 WELCOME ADDRESS
John COMMON, Conference Chair & Treasurer SRSS; SRIS
SESSION 1. WOUNDS
Chair: Zee UPTON, Skin Research Institute of Singapore (SRIS)
13:10 – 13:35 What do we know about the epidemiology and costs of
chronic wounds in Singapore?
Nick GRAVES, Duke-NUS, Singapore
13:35 – 13:47 Diabetic foot ulcer care – a DEFINITE WiCC-ked LEAPP in
wound care at National Healthcare Group
Enming YONG, Tan Tock Seng Hospital, Singapore
13:47 – 13:59 SRIS Skin metabolomics platform – mass spectrometry for
interrogating skin biology
Sze Han LEE, Skin Research Institute of Singapore
13:59 – 14:11 Selected abstract
Development of perturbed wound model in rats and pigs
Jiah Shin CHIN, Nanyang Technological University, Singapore
14:11 – 14:23 Selected abstract
Multifunctional CaproGlu tissue adhesives for prevention and
detection of wound infection
Elizabeth ELLIS, Nanyang Technological University, Singapore
14:23 – 14:48 Flightless I regulation of wound healing and inflammation
Allison COWIN, University of South Australia, Australia
14:48 – 15:13 Research highlights from SKINTEGRITY.CH - a Swiss
interdisciplinary skin research consortium
Sabine WERNER, ETZ Zürich, Switzerland
15:13 – 15:45 BREAK
SESSION 2. ATOPIC DERMATITIS
Chairs: John COMMON, SRIS & Steven THNG, National Skin Centre, Singapore
15:45 – 16:10 Developmental cell programs in inflammatory skin disease
Muzlifah HANIFFA, Newcastle University, UK
16:10 – 16:22 Selected abstract
Percutaneous sensitization is limited by skin regulatory T cells
via in situ IL-10 production
Sho HANAKAWA, Skin Research Institute of Singapore
16:22 – 16:34 Selected abstract
Immunophenotypes underlying skin endotypes of Atopic
Dermatitis in Singapore
Anand Kumar ANDIAPPAN, Singapore Immunology Network,
Singapore
16:34 – 16:46 Selected abstract
Imaging toolbox for skin: Three-dimensional optical clearing
and imaging of pruritic atopic dermatitis and psoriasis skin as a
case study
Yingrou TAN, Singapore Immunology Network, Singapore
16:46 – 16:58 Selected abstract
Relationship of atopic dermatitis with obesity and its related
inflammatory metabolic disturbances in an adult general
population cohort
Yik Weng YEW, National Skin Centre & LKCMedicine, NTU,
Singapore
16:58 – 17:23 From genome-wide association to molecular mechanisms in
atopic eczema
Sara BROWN, University of Edinburgh, UK
17:23 – 17:48 Formation and functions of high endothelial venule-like vessels
in the skin of atopic dermatitis
Tetsuya HONDA, Hamamatsu University School of Medicine,
Japan
17:50 END OF DAY 1
13:00 – 13:10 WELCOME ADDRESS
John COMMON, Conference Chair & Treasurer SRSS; SRIS
SESSION 1. WOUNDS
Chair: Zee UPTON, Skin Research Institute of Singapore (SRIS)
13:10 – 13:35 What do we know about the epidemiology and costs of
chronic wounds in Singapore?
Nick GRAVES, Duke-NUS, Singapore
13:35 – 13:47 Diabetic foot ulcer care – a DEFINITE WiCC-ked LEAPP in
wound care at National Healthcare Group
Enming YONG, Tan Tock Seng Hospital, Singapore
13:47 – 13:59 SRIS Skin metabolomics platform – mass spectrometry for
interrogating skin biology
Sze Han LEE, Skin Research Institute of Singapore
13:59 – 14:11 Selected abstract
Development of perturbed wound model in rats and pigs
Jiah Shin CHIN, Nanyang Technological University, Singapore
14:11 – 14:23 Selected abstract
Multifunctional CaproGlu tissue adhesives for prevention and
detection of wound infection
Elizabeth ELLIS, Nanyang Technological University, Singapore
14:23 – 14:48 Flightless I regulation of wound healing and inflammation
Allison COWIN, University of South Australia, Australia
14:48 – 15:13 Research highlights from SKINTEGRITY.CH - a Swiss
interdisciplinary skin research consortium
Sabine WERNER, ETZ Zürich, Switzerland
15:13 – 15:45 BREAK
SESSION 2. ATOPIC DERMATITIS
Chairs: John COMMON, SRIS & Steven THNG, National Skin Centre, Singapore
15:45 – 16:10 Developmental cell programs in inflammatory skin disease
Muzlifah HANIFFA, Newcastle University, UK
16:10 – 16:22 Selected abstract
Percutaneous sensitization is limited by skin regulatory T cells
via in situ IL-10 production
Sho HANAKAWA, Skin Research Institute of Singapore
16:22 – 16:34 Selected abstract
Immunophenotypes underlying skin endotypes of Atopic
Dermatitis in Singapore
Anand Kumar ANDIAPPAN, Singapore Immunology Network,
Singapore
16:34 – 16:46 Selected abstract
Imaging toolbox for skin: Three-dimensional optical clearing
and imaging of pruritic atopic dermatitis and psoriasis skin as a
case study
Yingrou TAN, Singapore Immunology Network, Singapore
16:46 – 16:58 Selected abstract
Relationship of atopic dermatitis with obesity and its related
inflammatory metabolic disturbances in an adult general
population cohort
Yik Weng YEW, National Skin Centre & LKCMedicine, NTU,
Singapore
16:58 – 17:23 From genome-wide association to molecular mechanisms in
atopic eczema
Sara BROWN, University of Edinburgh, UK
17:23 – 17:48 Formation and functions of high endothelial venule-like vessels
in the skin of atopic dermatitis
Tetsuya HONDA, Hamamatsu University School of Medicine,
Japan
17:50 END OF DAY 1
THURSDAY, 25th February - DAY 2
SESSION 3. RAPID-FIRE TALKS I
Chair: Baptiste JANELA, SRIS & Srikala RAGHAVAN, SRIS
11:30 – 12:30 Rapid-fire talk presentations (5mins each)
Speakers:
12:30 – 13:00 BREAK
Session 4. AGING - This session is supported by Johnson & Johnson
Chair: Oliver DREESEN, SRIS
13:00 – 13:25 Molecular determinants of endothelial progenitor plasticity:
new targets for skin fibrosis
Kiarash KHOSROTEHRANI, Diamantina Institute, University of
Queensland, Australia
13:25 – 13:37 Selected abstract
Delineating the chain of events that trigger premature cell
aging in Hutchinson-Gilford Progeria Syndrome
Mattheus Xing Rong FOO, Skin Research Institute of Singapore
13:37 – 13:49 Selected abstract
Investigating the molecular mechanism underlying
polyamine promotion of wound healing
Meng SHI, Skin Research Institute of Singapore
13:49 – 14:01 Selected abstract
Nicotinamide prevents UVB- and oxidative stress-induced
photoaging in human primary keratinocytes
Malgorzata MORENC, Skin Research Institute of Singapore
14:01 – 14:13 Selected abstract
Identification and quantification of senescent cells in UV-
induced skin pathologies
Audrey Shimei WANG, Skin Research Institute of Singapore
14:13 – 14:38 Selective inhibition of DNA damage response activation at
telomeres improves skin aging in a progeric mouse models
Fabrizio D’ADDA DI FAGAGNA, IFOM, Milan, Italy
14:38 – 15:03 Skin stem cells shuffle sugars as they age: glycome profiling
reveals dynamic glycan alterations during epidermal stem
cell aging
Aiko SADA, Kumamoto University, Japan
15:03 – 15:30 BREAK
SESSION 5. PIGMENTATION
Chairs: Leah VARDY, SRIS & Carlos CLAVEL, SRIS
15:30 – 15:55 Functional melanoma cell heterogeneity is regulated by
MITF-dependent cell-matrix interactions
Nikolas HAASS, Diamantina Institute, University of
Queensland, Australia
15:55 – 16:07 Selected abstract
Elucidating the role of polyamines in human pigmentation
Xenia KODJI, Skin Research Institute of Singapore
16:07 – 16:19 Selected abstract
Effects of BMP signaling in epidermal re-pigmentation
during phototherapy for vitiligo
Jamien LIM, Skin Research Institute of Singapore
16:19 – 16:31 Selected abstract
Effect of pollution on skin pigmentation
Rachel PHUA, Skin Research Institute of Singapore
16:31 – 16:43 Selected abstract
Protein nanocages for cutaneous delivery of active
ingredients for antiaging and pigmentation
Sathya Moorthy BHASKAR, Nanyang Technological
University, Singapore
16:43 – 17:08 Melanin in human skin epidermis - quo vadis?
Desmond TOBIN, University College Dublin, Ireland
17:08 – 17:33 Genomic and functional analysis of variation in human
pigmentation
Ian JACKSON, The University of Edinburgh, United Kingdom
17:33 – 17:48 Industry themed talk
Deep characterisation of tumor and tissue
microenvironment
Boon-Eng TEH, Fluidigm, Singapore
17:50 END OF DAY 2
Chair: Baptiste JANELA, SRIS & Srikala RAGHAVAN, SRIS
11:30 – 12:30 Rapid-fire talk presentations (5mins each)
Speakers:
- Mary B. Chan-Park, Nanyang Technological University, Singapore
- Naren Kumar Surendra, Nanyang Technological University, Singapore
- Gowtham Subramanian, Skin Research Institute of Singapore
- Ruth Chai, Institute of Molecular and Cell Biology, Singapore
- Fazila Aloweni, Singapore General Hospital
- Nanthakumahrie Gunasegaran, Singapore General Hospital
- Jingwei Xiong, Skin Research Institute of Singapore
- Colin Wong, Skin Research Institute of Singapore
- Yee Yee Chang, Singapore General Hospital
- Priya Bishnoi, Skin Research Institute of Singapore
- Shree Harsha Vijaya Chandra, Skin Research Institute of Singapore
- Tong San Tan, Skin Research Institute of Singapore
12:30 – 13:00 BREAK
Session 4. AGING - This session is supported by Johnson & Johnson
Chair: Oliver DREESEN, SRIS
13:00 – 13:25 Molecular determinants of endothelial progenitor plasticity:
new targets for skin fibrosis
Kiarash KHOSROTEHRANI, Diamantina Institute, University of
Queensland, Australia
13:25 – 13:37 Selected abstract
Delineating the chain of events that trigger premature cell
aging in Hutchinson-Gilford Progeria Syndrome
Mattheus Xing Rong FOO, Skin Research Institute of Singapore
13:37 – 13:49 Selected abstract
Investigating the molecular mechanism underlying
polyamine promotion of wound healing
Meng SHI, Skin Research Institute of Singapore
13:49 – 14:01 Selected abstract
Nicotinamide prevents UVB- and oxidative stress-induced
photoaging in human primary keratinocytes
Malgorzata MORENC, Skin Research Institute of Singapore
14:01 – 14:13 Selected abstract
Identification and quantification of senescent cells in UV-
induced skin pathologies
Audrey Shimei WANG, Skin Research Institute of Singapore
14:13 – 14:38 Selective inhibition of DNA damage response activation at
telomeres improves skin aging in a progeric mouse models
Fabrizio D’ADDA DI FAGAGNA, IFOM, Milan, Italy
14:38 – 15:03 Skin stem cells shuffle sugars as they age: glycome profiling
reveals dynamic glycan alterations during epidermal stem
cell aging
Aiko SADA, Kumamoto University, Japan
15:03 – 15:30 BREAK
SESSION 5. PIGMENTATION
Chairs: Leah VARDY, SRIS & Carlos CLAVEL, SRIS
15:30 – 15:55 Functional melanoma cell heterogeneity is regulated by
MITF-dependent cell-matrix interactions
Nikolas HAASS, Diamantina Institute, University of
Queensland, Australia
15:55 – 16:07 Selected abstract
Elucidating the role of polyamines in human pigmentation
Xenia KODJI, Skin Research Institute of Singapore
16:07 – 16:19 Selected abstract
Effects of BMP signaling in epidermal re-pigmentation
during phototherapy for vitiligo
Jamien LIM, Skin Research Institute of Singapore
16:19 – 16:31 Selected abstract
Effect of pollution on skin pigmentation
Rachel PHUA, Skin Research Institute of Singapore
16:31 – 16:43 Selected abstract
Protein nanocages for cutaneous delivery of active
ingredients for antiaging and pigmentation
Sathya Moorthy BHASKAR, Nanyang Technological
University, Singapore
16:43 – 17:08 Melanin in human skin epidermis - quo vadis?
Desmond TOBIN, University College Dublin, Ireland
17:08 – 17:33 Genomic and functional analysis of variation in human
pigmentation
Ian JACKSON, The University of Edinburgh, United Kingdom
17:33 – 17:48 Industry themed talk
Deep characterisation of tumor and tissue
microenvironment
Boon-Eng TEH, Fluidigm, Singapore
17:50 END OF DAY 2
FRIDAY, 26th February - DAY 3
SESSION 6. RAPID-FIRE TALKS II
Chair: Chin Yan LIM, SRIS & Srikala RAGHAVAN, SRIS
11:30 – 12:30 Rapid-fire talk presentations (5mins each)
Speakers:
13. Shan Quah, Skin Research Institute of Singapore
14. Dang Nguyen, School of Chemical and Biomedical Engineering
15. Kamaladasan Kalidasan, Skin Research Institute of Singapore
16. Sivagame Maniya, Sengkang General Hospital
17. Bhavya Sharma, Skin Research Institute of Singapore
18. Aneesh Karkhanis, Skin Research Institute of Singapore
19. Aishwarya Sridharan, Skin Research Institute of Singapore
20. Paul Hiebert, ETH Zurich
21. Jayakumar Perumal, Singapore Bioimaging Consortium
22. Juhi Singh, Nanyang Technological University
23. Chidambaran Natesavelalar, Skin Research Institute of Singapore
12:30 – 13:00 BREAK
SESSION 7. HAIR BIOLOGY
Chairs: Etienne WANG, National Skin Centre & Birgit LANE, SRIS
13:00 – 13:25 Regulation of hair regeneration by dermal fibroblast lineages
Maksim PLIKUS, University of California, Irvine, USA
13:25 – 13:37 Selected abstract
Modelling epigenetic changes regulating hair follicle induction
Nikolaos PANTELIREIS, Imperial College London, London, UK
13:37 – 13:49 Selected abstract
Sox2 in the dermal papilla regulates hair follicle pigmentation
Krystle Joy NG, Skin Research Institute of Singapore
13:49 – 14:01 Selected abstract
Junctional instability overrides intrinsic quiescence of bulge
stem cells
Avinanda BANERJEE, Skin Research Institute of Singapore
14:01 – 14:13 Selected abstract
Senescence-induced hair follicle stem cells undergo a change
of fate in mouse model
Zoe LIM, Skin Research Institute of Singapore
14:13 – 14:38 Hairy strategies for skin regeneration
Claire HIGGINS, Imperial College London, UK
14:38 – 15:03 JAKpot: new therapies for Alopecia Areata
Angela CHRISTIANO, Columbia University, USA
15:03 – 15:35 BREAK
SESSION 8. HOST-MICROBE INTERACTIONS
Chairs: Niranjan NAGARAJAN, Genome Institute of Singapore & Kenji
KABASHIMA, Kyoto University, Japan & SRIS
15:35 – 16:00 The skin commensal yeast Malassezia at the interface of
health and disease
Salome LEIBUNDGUT-LANDMANN, University of Zürich,
Switzerland
16:00 – 16:12 Selected abstract
Distinct skin microbiome ‘fingerprints’ in congenital ichthyosis
Khek-Chian THAM, Skin Research Institute of Singapore
16:12 – 16:24 Selected abstract
Tetraspanin-derived peptides reduce adherence of S. aureus in
human skin models
Nathan WONG, University of Sheffield, UK & Skin Research
Institute of Singapore
16:24 – 16:36 Selected abstract
A non-invasive, mass-spectrometry based method for
quantification of human skin eicosanoids and Malassezia
oxylipins as a tool to explore host/mycobiome interactions
Martin PAGAC, Skin Research Institute of Singapore
16:36 – 16:48 Selected abstract
Shared signatures and divergence in skin microbiomes of
children with atopic dermatitis and their adult caregivers
Minghao CHIA, Genome Institute of Singapore
16:48 – 17:13 Dermal white adipose tissue: a newly recognized layer of skin
innate defense
Ling-Juan ZHANG, Xiamen University, China
17:13 – 17:38 Skin colonized Staphylococcus aureus increases the
susceptibility to inflammation via innate immune pathways
Saeko NAKAJIMA, Kyoto University Graduate School of
Medicine, Japan
17:40 POSTER PRIZE AWARDS & CLOSING REMARKS
Oliver DREESEN, President SRSS; Conference Co-chair; SRIS
END OF DAY 3 & FAREWELL
Chair: Chin Yan LIM, SRIS & Srikala RAGHAVAN, SRIS
11:30 – 12:30 Rapid-fire talk presentations (5mins each)
Speakers:
13. Shan Quah, Skin Research Institute of Singapore
14. Dang Nguyen, School of Chemical and Biomedical Engineering
15. Kamaladasan Kalidasan, Skin Research Institute of Singapore
16. Sivagame Maniya, Sengkang General Hospital
17. Bhavya Sharma, Skin Research Institute of Singapore
18. Aneesh Karkhanis, Skin Research Institute of Singapore
19. Aishwarya Sridharan, Skin Research Institute of Singapore
20. Paul Hiebert, ETH Zurich
21. Jayakumar Perumal, Singapore Bioimaging Consortium
22. Juhi Singh, Nanyang Technological University
23. Chidambaran Natesavelalar, Skin Research Institute of Singapore
12:30 – 13:00 BREAK
SESSION 7. HAIR BIOLOGY
Chairs: Etienne WANG, National Skin Centre & Birgit LANE, SRIS
13:00 – 13:25 Regulation of hair regeneration by dermal fibroblast lineages
Maksim PLIKUS, University of California, Irvine, USA
13:25 – 13:37 Selected abstract
Modelling epigenetic changes regulating hair follicle induction
Nikolaos PANTELIREIS, Imperial College London, London, UK
13:37 – 13:49 Selected abstract
Sox2 in the dermal papilla regulates hair follicle pigmentation
Krystle Joy NG, Skin Research Institute of Singapore
13:49 – 14:01 Selected abstract
Junctional instability overrides intrinsic quiescence of bulge
stem cells
Avinanda BANERJEE, Skin Research Institute of Singapore
14:01 – 14:13 Selected abstract
Senescence-induced hair follicle stem cells undergo a change
of fate in mouse model
Zoe LIM, Skin Research Institute of Singapore
14:13 – 14:38 Hairy strategies for skin regeneration
Claire HIGGINS, Imperial College London, UK
14:38 – 15:03 JAKpot: new therapies for Alopecia Areata
Angela CHRISTIANO, Columbia University, USA
15:03 – 15:35 BREAK
SESSION 8. HOST-MICROBE INTERACTIONS
Chairs: Niranjan NAGARAJAN, Genome Institute of Singapore & Kenji
KABASHIMA, Kyoto University, Japan & SRIS
15:35 – 16:00 The skin commensal yeast Malassezia at the interface of
health and disease
Salome LEIBUNDGUT-LANDMANN, University of Zürich,
Switzerland
16:00 – 16:12 Selected abstract
Distinct skin microbiome ‘fingerprints’ in congenital ichthyosis
Khek-Chian THAM, Skin Research Institute of Singapore
16:12 – 16:24 Selected abstract
Tetraspanin-derived peptides reduce adherence of S. aureus in
human skin models
Nathan WONG, University of Sheffield, UK & Skin Research
Institute of Singapore
16:24 – 16:36 Selected abstract
A non-invasive, mass-spectrometry based method for
quantification of human skin eicosanoids and Malassezia
oxylipins as a tool to explore host/mycobiome interactions
Martin PAGAC, Skin Research Institute of Singapore
16:36 – 16:48 Selected abstract
Shared signatures and divergence in skin microbiomes of
children with atopic dermatitis and their adult caregivers
Minghao CHIA, Genome Institute of Singapore
16:48 – 17:13 Dermal white adipose tissue: a newly recognized layer of skin
innate defense
Ling-Juan ZHANG, Xiamen University, China
17:13 – 17:38 Skin colonized Staphylococcus aureus increases the
susceptibility to inflammation via innate immune pathways
Saeko NAKAJIMA, Kyoto University Graduate School of
Medicine, Japan
17:40 POSTER PRIZE AWARDS & CLOSING REMARKS
Oliver DREESEN, President SRSS; Conference Co-chair; SRIS
END OF DAY 3 & FAREWELL