SATURDAY 24^TH MARCH - DAY 4

08.30 – 09:00

REGISTRATION

09.00 – 10.45

SESSION 10: SKIN BARRIER DEVELOPMENT & INTEGRITY

Chairs: So Yun CHO, Director of Board of Members of KSBR

Leah VARDY, Institute of Medical Biology, Singapore

09.00 – 09.30

Akiharu Kubo, Keio University School of Medicine, Tokyo, Japan
Tight but dynamic: The sophisticated barrier system of mammalian skin

09.30 – 09.45

Li HE, Institute of Dermatology & Venereology of Yunnan province, Kunming, China
MicroRNA-224-5p induced claudin-5 deficiency contributes to defective permeability barrier in sensitive skin

09.45 – 10.00

Kento Kitada, DUKE-NUS Medical School, Singapore
Increased glucocorticoid hormone actions via melanocortin 3 receptor

deletion induce skin-specific Na⁺ and water loss

10.00 – 10.15

Anisa RAHIM, Institute of Medical Biology, Singapore
Unravelling gene regulation in the epidermis during differentiation

10.15 – 10.45

Florent GINHOUX, Singapore Immunology Network, Singapore
Human dendritic cells: From development to functions.

10.45 – 11.15

Morning tea break

11.15 – 13.00

SESSION 11: Skin Barrier & THE IMMUNE SYSTEM

Chairs: Chih-Hung (Abel) LEE, Kaohsiung Chang Gung Memorial Hospital, Taiwan

Kenji KABASHIMA, Department of Dermatology, University of Kyoto, Japan

11.15 – 11.45

Chang Ook PARK, Yonsei University College of Medicine, Seoul, Korea
Tissue-resident memory T cells as an immune barrier

11.45 – 12.00

Rintaro Shibuya, Kyoto University Graduate School of Medicine, Japan
Complement activation increases susceptibility to surfactant-induced irritant contact dermatitis

12.00 – 12.15

Anand Kumar Andiappan, Singapore Immunology Network, Singapore
Whole transcriptome analysis of peripheral blood reveals strong

proinflammatory signatures associated with skin relevant FLG mutants

12.15 – 12.30

Jiajia MA, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
A proteolytic regulator of epidermal integrity and inflammation

12.30 – 13.00

Franklin ZHONG, Institute of Medical Biology, Singapore
NLRP1 inflammasome in skin inflammation and cancer susceptibility

13.00

END OF CONFERENCE